Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019474
Fusion event
HBV-MMP16 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Host Sequence
Chromosome
chr8
Cytoband
q21.3
Reference genome
Start
End
89240949/88228720 (Hg38)
Location type
Intron9
Target gene
miRNAs that regulate target gene
hsa-mir-146b-5p ; hsa-mir-31-5p ; hsa-mir-328-3p ; hsa-mir-155-5p ; hsa-mir-218-5p ; hsa-mir-4712-3p ; hsa-mir-548at-5p ; hsa-mir-3924 ; hsa-mir-190a-3p ; hsa-mir-325 ; hsa-mir-628-3p ; hsa-mir-487a-3p ; hsa-mir-154-3p ; hsa-mir-5011-5p ; hsa-mir-1277-5p ; hsa-let-7c-3p ; hsa-mir-7158-5p ; hsa-mir-3171 ; hsa-mir-29b-1-5p ; hsa-mir-767-3p ; hsa-mir-4502 ; hsa-mir-4693-5p ; hsa-mir-892a ; hsa-mir-4318 ; hsa-mir-6796-3p ; hsa-mir-99b-3p ; hsa-mir-99a-3p ; hsa-mir-145-3p
Nearest miRNA
hsa-mir-12123/Upstream/7987246; hsa-mir-10400/Downstream/2976765;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/354502, chr8-CpG: 25/Downstream/99176
Upstream sequence
ATATAAGCTCATGTCATtcaggaccattttagttataagtgaaagaaaaccacaatcaaatttacttttggaaggtatatattggcttagataattgaaa
Downstream sequence
cctttgctcacaaatacagcctgaaatagtctgcatgtatcagaaggcaactattaagtaaactttggaacattcttactaggctattgtggagtcaata
Target sequence
c
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.