Basic Information
VIS ID
TVIS10019488
Fusion event
HBV-chr8 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr8
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
60291543/59378984 (Hg38)
End
60291556/59378997 (Hg38)
Nearest miRNA
hsa-mir-124-1/Upstream/16482709; hsa-mir-10400/Downstream/2335791;
Nearest TSS
ENST00000518652/Upstream/259038; ENST00000522898/Downstream/214704;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/258797, chr8-CpG: 14/Downstream/794569
Nearby gene
TOX
Upstream sequence
ggtattcttttcatcatttcacagTACTGTGTGACTTGAGCAGCTCTGGAAGCTAGGAAACACATACTGTGAGGGGAAAATAAGTAAGAGACATACTTTG
Downstream sequence
acaaacaaaaaCCCACAAAAAACAAATATGCATAAACACAACAGAAAAGAAAATGACAAAGAAGTTTCCAATAAACTATTGGATGGGAAGCTGATGGAGA
Target sequence
ttgtctaaaataa
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate