DLG2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019494
Fusion event
HBV-DLG2 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr11
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
85195010/85483966 (Hg38)
End
85195230/85484186 (Hg38)
Location type
Intron25
Target gene
DLG2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-148b-3p
Nearest miRNA
hsa-mir-10392/Upstream/3593130; hsa-let-7a-2/Downstream/794147;
Nearest TSS
ENST00000527297/Upstream/350843; ENST00000530901/Downstream/40836;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/2197473, chr11-CpG: 24/Downstream/144113
Upstream sequence
ACCTCTTCTACACTCTCTGAATCCCATTAGTCCTCCAGGATGTGGACTGTGCCTCCAGGACCCCTCTCACAGCTAACCCCTTCCCTTAACGGCCATTAGC
Downstream sequence
gatctttcccgccccccgttcctcccgacccctccacccgccctccctctcccaccgcccctcctcctcctccctaggcattaccattcaggacataggc
Target sequence
Ggcccgggtcttccaggagtcgggttgcttgggaatgcagcccaaagcgggtggtaaactccatttaaggctaaataccggcacgagaccgatagtcaacaagtaccgtaagggaaagttgaaaagaactttgaagagagagtacaagagggcgtgaaaccgttaagaggtaaatgggtcaggtccgcgcagtccgcccggaggattcaacccggtggcg
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate