VISDB Viral Integration Site DataBase

VIS ID

TVIS10019507

Fusion event

HBV-LAPTM4A integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Chromosome

chr2

Cytoband

p24.1

Reference genome

Start

End

20233041/20033280 (Hg38)

Location type

Exon1

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-17-5p ; hsa-mir-410-3p ; hsa-mir-20a-5p ; hsa-mir-106b-5p ; hsa-mir-190a-3p ; hsa-mir-340-5p ; hsa-mir-143-5p ; hsa-mir-5590-3p ; hsa-mir-142-5p ; hsa-mir-4496 ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-651-3p ; hsa-mir-186-5p ; hsa-mir-3133 ; hsa-mir-106a-5p ; hsa-mir-526b-3p ; hsa-mir-93-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-891a-3p ; hsa-mir-3688-5p ; hsa-mir-6809-5p ; hsa-mir-31-5p ; hsa-mir-4698 ; hsa-mir-299-3p ; hsa-mir-4657 ; hsa-mir-4491

Nearest miRNA

hsa-mir-3125/Upstream/684260; hsa-mir-10b/Downstream/5295360;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/19743, chr2-CpG: 52/Downstream/18153

Upstream sequence

ACATATTGAACACAATCTCAGGGACTATTTCACGCAATAGCAAATGTCTCTTCAACTACAGAGATGGAAAGCAAAATAGAAAACTAGTTTCATGAAGGGA

Downstream sequence

TAAAGAGAGAAAAAAAATTGTATCAGATTTAATTCTCCTTTAAAATCCTTTGTGAGATAATTCAGCTTTCAGACTTTATGCCCTAAATAGGGTTATACAA

Target sequence

GCCTCTGCAGATGAAAAGTTCAGATCTTATACCCAACTACTTACTCACCCCGAATATTTAAGTCAGTCTTCCTGAAAGTACTCAGGGTAGCAAGTAACAAAATGCAAACGATTATATAAAGAAAGTGCAGTTAAAAAGGAAACTATGTGGCAAGTACCCTCTTTCCCTTCCCACCCCCCAATTAAAGGCAAACAATGGCACTTTGCTCTTGCTTAACCTAGATTGTCTTCAAAAACTATTAAAATGTAAAAGACT