VISDB Viral Integration Site DataBase

VIS ID

TVIS10019512

Fusion event

HBV-chr6 integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Chromosome

chr6

Cytoband

q13

Reference genome

Start

End

74228190/73518467 (Hg38)

Location type

Exonic

Fragile sites / regions

Target gene

EEF1A1 ; SNORD141A ; SNORD141B

miRNAs that regulate target gene

hsa-mir-16-5p ; hsa-mir-1226-3p ; hsa-mir-877-5p ; hsa-mir-455-3p ; hsa-mir-361-3p ; hsa-mir-296-3p ; hsa-mir-93-3p ; hsa-mir-421 ; hsa-mir-652-3p ; hsa-mir-615-3p ; hsa-mir-505-3p ; hsa-mir-501-5p ; hsa-mir-497-5p ; hsa-mir-484 ; hsa-mir-423-3p ; hsa-mir-339-5p ; hsa-mir-324-3p ; hsa-mir-340-3p ; hsa-mir-30e-5p ; hsa-mir-106b-5p ; hsa-mir-186-5p ; hsa-mir-185-5p ; hsa-mir-125a-5p ; hsa-mir-125b-5p ; hsa-mir-23b-3p ; hsa-mir-15b-5p ; hsa-let-7g-5p ; hsa-mir-221-3p ; hsa-mir-30c-5p ; hsa-mir-197-3p ; hsa-mir-100-5p ; hsa-mir-96-5p ; hsa-mir-93-5p ; hsa-mir-92a-3p ; hsa-mir-30a-5p ; hsa-mir-26b-5p ; hsa-mir-25-3p ; hsa-mir-24-3p ; hsa-mir-18a-5p ; hsa-mir-17-5p ; hsa-let-7b-5p ; hsa-mir-1260b ; hsa-mir-4441 ; hsa-mir-4776-3p ; hsa-mir-6516-5p ; hsa-mir-4659b-5p ; hsa-mir-4659a-5p ; hsa-mir-5590-5p ; hsa-mir-765 ; hsa-mir-6499-3p ; hsa-mir-4784 ; hsa-mir-3150b-3p ; hsa-mir-5186 ; hsa-mir-6840-3p ; hsa-mir-665 ; hsa-mir-6888-5p ; hsa-mir-4459 ; hsa-mir-6732-5p ; hsa-mir-7150 ; hsa-mir-4736 ; hsa-mir-4763-3p ; hsa-mir-1207-5p ; hsa-mir-4328 ; hsa-mir-4457 ; hsa-mir-4482-3p ; hsa-mir-4731-3p ; hsa-mir-4801 ; hsa-mir-7159-3p

Nearest miRNA

hsa-mir-10398/Upstream/550625; hsa-mir-10524/Downstream/1909940;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/56232, chr6-CpG: 135/Downstream/1772

Nearest cancer related gene

EEF1A1(OG, No orient, 0)

Upstream sequence

AGAGAAGTGGGATTCAGGGCGGCTGTGTCTTTAAATTAGAATCCTTGAGGCCTGGATTCCCTTCTTTGCTGCCTCCCACTTTTCCTCCTTCAGCAGCTCT

Downstream sequence

CCCAGGAAGAGCTTCACTCAAAGCTTCATGGTGCATTTCGACAGATTTTACTTCCGTTGTAACGTTGACTGGAGCAAAGGTGACCACCATACCGGGTTTG

Target sequence

ATTGGTGGGTCATTTTTGCTGTCACCAGCAACGTTGCCACGACGAACATCCTTGACAGACACATTCTTGACATTGAAGCCCACATTGTC