CNOT2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019515
Fusion event
HBV-CNOT2 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr12
Cytoband
q15
Reference genome
GRCh37/hg19
Start
70648354/70254574 (Hg38)
End
70648354/70254574 (Hg38)
Location type
Intron1
Target gene
CNOT2
miRNAs that regulate target gene
hsa-mir-301b-3p ; hsa-mir-361-5p ; hsa-let-7b-5p ; hsa-mir-7703 ; hsa-mir-4325 ; hsa-mir-889-3p ; hsa-mir-548au-3p ; hsa-mir-92b-3p ; hsa-mir-92a-3p ; hsa-mir-367-3p ; hsa-mir-363-3p ; hsa-mir-32-5p ; hsa-mir-25-3p ; hsa-mir-5003-3p ; hsa-mir-935 ; hsa-mir-9500 ; hsa-mir-1264
Nearest miRNA
hsa-let-7i/Upstream/669751; hsa-mir-1178/Downstream/9164683;
Nearest TSS
ENST00000382841/Upstream/10823; ENST00000547867/Downstream/23558;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/10605, chr12-CpG: 144/Downstream/111083
Upstream sequence
agttgggaggatgaggcaggagaatcacttgaatccaggaggtggaggttgcagtgagctgagatcatgccattgcactccagcctggacaacagaatga
Downstream sequence
AGAGGTAAATAGGGAAACATTAAAGTGGTGTGATTTGGAGCCGCATTACAGCCAAGAGATAGGGAAGGACATTCCAGGAATGGAAGACATATACATGAAG
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate