VISDB Viral Integration Site DataBase

VIS ID

TVIS10019518

Fusion event

HBV-ORMDL3 integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Chromosome

chr17

Cytoband

q21.1

Reference genome

Start

End

38078198/39921945 (Hg38)

Location type

Exon1

Target gene

miRNAs that regulate target gene

hsa-mir-20a-5p ; hsa-mir-6771-3p ; hsa-mir-106b-5p ; hsa-mir-1229-3p ; hsa-mir-155-3p ; hsa-mir-197-3p ; hsa-mir-4713-3p ; hsa-mir-6862-3p ; hsa-mir-6784-3p ; hsa-mir-6511b-3p ; hsa-mir-6511a-3p ; hsa-mir-4700-3p ; hsa-mir-140-3p ; hsa-mir-4665-5p ; hsa-mir-1275 ; hsa-mir-5010-5p ; hsa-mir-4525 ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-5698 ; hsa-mir-4723-5p ; hsa-mir-625-5p ; hsa-mir-6780b-5p ; hsa-mir-4725-3p ; hsa-mir-4271 ; hsa-mir-637 ; hsa-mir-5695 ; hsa-mir-4715-5p ; hsa-mir-3691-3p ; hsa-mir-508-5p ; hsa-mir-3145-5p ; hsa-mir-4653-3p ; hsa-mir-6778-3p ; hsa-mir-4424 ; hsa-mir-4667-3p ; hsa-mir-1470 ; hsa-mir-519d-3p ; hsa-mir-93-5p ; hsa-mir-17-5p ; hsa-mir-20b-5p

Nearest miRNA

hsa-mir-1180/Upstream/195118; hsa-mir-10226/Downstream/104387;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/53295, chr17-CpG: 78/Downstream/5028

Upstream sequence

CTCTACAGGGTGTTTAGTGTGATGTTTGGATCACTTTCGAAGAGCGTTTAACATTTCTCCTTCTTACACTTTCGAAGAGCGTTTAACATTTCTCCTTCTT

Downstream sequence

CCCCAACCTGACCCTCCCCACTCCCAACCAGGACCCACGGTGGGTTGCAGAGAAGCTGCCAAAAGCCTGGGACTTGGATTAGACAGCTCCCTACCCAGAA

Target sequence

CTCCCCTATTACTATCACATTCTGTGGGTAAATTAACCCTCCAAGCCTGCTTCCCTCCCTGCCCACATCCCAAAGGAGATTGGGTCTAGCTTCTGTCCCTACCCCTCCCTCCCTTACACCAGTCCTCTGCTGCTATGTGGCCCCATTCTTCTAAGTCTCGACTCACTAGCTCTCCTACAGCTCCCCAACCTCCACCAGGCCAGGATGGCAGCAGCCCTGGCCCCCTCACCTCTGGAACCAAGCCATCTACACTCT