Basic Information
VIS ID
TVIS10019523
Fusion event
HBV-chr2 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr2
Cytoband
q13
Reference genome
GRCh37/hg19
Start
111250861/110493284 (Hg38)
End
111251603/110494026 (Hg38)
Fragile sites / regions
FRA2S ; FRA2B
Nearest miRNA
hsa-mir-1285-2/Upstream/208341; hsa-mir-10b/Downstream/826987;
Nearest TSS
ENST00000437798/Upstream/20209; ENST00000458252/Downstream/37104;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/69254, chr2-CpG: 99/Downstream/82353
Nearby gene
RGPD6
Upstream sequence
ttcttttcttttttttttttttttttttttttttttcttctttttctttttttttttttttttttttctttttttttttttcttcttttttttttttttt
Downstream sequence
cctgagaaatctgtgtgtcagtttggagtggaaaaggcagacccagtacaacataaaaaggaattgttggacctccaaaattctagcaggaagcaggctg
Target sequence
ctctgtcttgaaaaaaaaaaaggaacaaaaaCAATCTTAAACGAATAAGTAAATTTGGTTAAATAGTTGCACATGTTTTCTCTATGAACAGAAATCAGAAATGGAAATGGAAAACCATGTCATTGAATAGCAACTAAATTCAAAGTGAAATAAAAATAACATCAAGGACATGAGTTTAACTTGAATAAAATTTTGTAGTGGACGTTAAAActaagtacattgagagacaccgtatctgaatggggagactcacta
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate