Basic Information
VIS ID
TVIS10019525
Fusion event
HBV-chr2 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr2
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
113206353/112448776 (Hg38)
End
113206915/112449338 (Hg38)
Fragile sites / regions
FRA2S ; FRA2B
Nearest miRNA
hsa-mir-1285-2/Upstream/677642; hsa-mir-10b/Downstream/1133621;
Nearest TSS
ENST00000437798/Upstream/14288; ENST00000485537/Downstream/32816;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/15079, chr2-CpG: 167/Downstream/32334
Nearby gene
TTL
Upstream sequence
taaaaactatacagaagcattctcagaaacttctttgtgatatgtgtactcaactcacagagttgaacctttcttttgatatagcaattttgaaacactc
Downstream sequence
tcagattgtctcaaacaattaaacctctagggagcttaagagtatttttcctcagcctctcagcagaagctcaagatagtgaagggtttatccagagaga
Target sequence
aaaaaggaacaaaaaCAATCTTAAACGAATAAGTAAATTTGGTTAAATAGTTGCACATGTTTTCTCTATGAACAGAAATCAGAAATGGAAATGGAAAACCATGTCATTGAATAGCAACTAAATTCAAAGTGAAATAAAAATAACATCAGGGACATGAGTTTAACTTGAATAAAATTTTGTAGTGGACGTTAAAACTAAGTACATTGAGAGACACCGTATCTGAATGGGGAGACTCGCTATCATAGGAATAAAAAT
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate