ZRANB3 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019526
Fusion event
HBV-ZRANB3 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr2
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
136005076/135247506 (Hg38)
End
136005076/135247506 (Hg38)
Location type
Intron9
Fragile sites / regions
FRA2S ; FRA2F
Target gene
ZRANB3
miRNAs that regulate target gene
hsa-mir-6855-5p ; hsa-mir-5096 ; hsa-mir-3170 ; hsa-mir-4662a-5p ; hsa-mir-193b-5p ; hsa-mir-6890-5p ; hsa-mir-575 ; hsa-mir-4676-5p ; hsa-mir-6858-3p
Nearest miRNA
hsa-mir-1285-2/Upstream/389633; hsa-mir-10b/Downstream/417891;
Nearest TSS
ENST00000437798/Upstream/8645; ENST00000483021/Downstream/106122;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/194818, chr2-CpG: 36/Downstream/283894
Upstream sequence
CAAATATAGTTGACACCCTTAAGCATCTGGGGATTAAGATGCTAATCCCCACTCTTATTGGAAGTGTCACTCTCAGGATAGCAGCTTATTTTTCTATTAC
Downstream sequence
TTTTAAAACCCAAAGTAGTAAAAAAGAAAACGTTATTACTTATTATTATTTTTTTTTAGAGACATGGTCTTAGCCAGGTGCAGTGTCGCATGaagtggga
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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