Basic Information
VIS ID
TVIS10019528
Fusion event
HBV-chr4 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr4
Cytoband
p16.1
Reference genome
GRCh37/hg19
Start
6635844/6634117 (Hg38)
End
6635933/6634206 (Hg38)
Fragile sites / regions
FRA4A
Nearest miRNA
hsa-mir-378d-1/Upstream/710789; hsa-mir-12113/Downstream/676244;
Nearest TSS
ENST00000502981/Upstream/16669; ENST00000507420/Downstream/5885;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/70029, chr4-CpG: 122/Downstream/6261
Nearby gene
MRFAP1
Upstream sequence
CAAAATAGTCTCCATTTATTTGTCAGGGTTTCAATGAATAACGTCTCCTGGTTGTAATTTCAACATCATCAGACATAAAACCTGTGAGGGATTGAAGAAA
Downstream sequence
ccatgttggccaagctggcctcaaactcctgtgatctgcctgcctcggcctcccaaagtgctgagatgacgggcatgatccactgcgcctggccaaagca
Target sequence
cctgcctcagcctcccaagtagctgggatgacaggtgcccatcaccacgcctggctaatttttgtatttttagtagagacagagtttcg
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate