Basic Information
VIS ID
TVIS10019536
Fusion event
HBV-chr10 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr10
Cytoband
q23.31
Reference genome
GRCh37/hg19
Start
90884034/89124277 (Hg38)
End
90884123/89124366 (Hg38)
Fragile sites / regions
FRA10D
Nearest miRNA
hsa-mir-1265/Upstream/60866; hsa-mir-107/Downstream/468381;
Nearest TSS
ENST00000439456/Upstream/111595; ENST00000437032/Downstream/82948;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/132894, chr10-CpG: 42/Downstream/83432
Nearby gene
MIR4679-1
Upstream sequence
TCCATACATCTACCCCAAAGTGTAGTCAGAAGTGTTTGAAATAACCTACTTGTGTGAGTCTTATGCCTAGTAAAATATCTTTAAAGCCATATACAAGTCA
Downstream sequence
TCACGTTTTTGGTTCATATTCTGCCAAATGCTTATATTCACTAACATGGAGAGAGTTCATAACATTGCAAAAATTTACAAATCTTTTTTTTTTCTGTCAC
Target sequence
atttaagcagttcccctcgtagctaaaacccatcttattcctaccataccatacAGATTTCTCCTGGCCTCAGACTCTTTTGTAAATCC
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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