Basic Information
VIS ID
TVIS10019537
Fusion event
HBV-chr10 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr10
Cytoband
q25.1
Reference genome
GRCh37/hg19
Start
109339564/107579806 (Hg38)
End
109339653/107579895 (Hg38)
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Nearest miRNA
hsa-mir-107/Upstream/3311401; hsa-mir-202/Downstream/3318195;
Nearest TSS
ENST00000439456/Upstream/415272; ENST00000421481/Downstream/460804;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/414759, chr10-CpG: 80/Downstream/334543
Nearby gene
LINC01435
Upstream sequence
TATCTTCTGGGCATAACAAGTATTAAAATTTCTGTTTATTTTTTCCTTACTGTTAGGGAGAAGATTTTCTTATTTTGTATATGATGGTGTCGAGTATGAA
Downstream sequence
tggagctggcagtgagctgagatcgcgccattacactccagcctgggtgacagagcaagactccaactcaattaaaaaaaaaaaaatgatcacagaagag
Target sequence
atacaaaaattagccaggtgtggtggtgggcccctgtagtcccagctacttgggagactgaggcaggagaatcacatgaacctaggagg
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate