Fusion event
HBV-chr1 integration
Detection method
VirusFinder
Disease
Hepatocellular carcinoma (HCC)
End
118200706/117658084 (Hg38)
Nearest miRNA
hsa-mir-101-1/Upstream/563257; hsa-mir-1182/Downstream/28192503;
Upstream sequence
GGTAGTTCGGGCATGAAGAGTGCCCTCCACGTATTTAAGAGATAAAGATACAGCATTTTCTGGAAAGGACAATAGTCCTGCAAGTCCTCCATGCAGGAAC
Downstream sequence
GGAGTGTCCGTGCTGCTGATTGGGCTCAGGGCACAGGTGCTGCTGGATGGTGTTTGGTGCTTTATGTGGTAACCTATTTCCCCAACAGGACATCATGGCT
Target sequence
tgagctcataccatgtgccaggcattgggctacaaagatgaaaaagacatcaatccATTTTTATTTTTCAATATATTTCCCAGAACTTGTGTCATCTTA
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.