Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019556
Fusion event
HBV-LYZ integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Host Sequence
Chromosome
chr12
Cytoband
q15
Reference genome
Start
End
69742324/69348544 (Hg38)
Location type
Exon1
Target gene
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-4668-5p ; hsa-mir-6720-5p ; hsa-mir-7703 ; hsa-mir-6512-3p ; hsa-mir-6729-5p ; hsa-mir-4649-5p ; hsa-mir-1273a ; hsa-mir-661 ; hsa-mir-873-3p ; hsa-mir-4486 ; hsa-mir-766-3p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-939-3p ; hsa-mir-6849-3p ; hsa-mir-3613-3p ; hsa-mir-508-5p ; hsa-mir-1247-3p ; hsa-mir-1273g-3p ; hsa-mir-3689d ; hsa-mir-377-5p ; hsa-mir-4252 ; hsa-mir-4537 ; hsa-mir-455-3p ; hsa-mir-4793-3p ; hsa-mir-5186 ; hsa-mir-6086 ; hsa-mir-6134 ; hsa-mir-6499-3p ; hsa-mir-6516-5p ; hsa-mir-6799-5p ; hsa-mir-6851-5p ; hsa-mir-6880-5p ; hsa-mir-7847-3p
Nearest miRNA
hsa-let-7i/Upstream/75326; hsa-mir-1178/Downstream/236178;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/108229, chr12-CpG: 57/Downstream/11181
Upstream sequence
ACCACCCCATTGGTCTCCATGTTGGTGAGGTTACCCCGCAGGTTCTGCTCCTCCTCGAAAGCCTTGAACAGTGAGTTGAAGTTGCCGGCTCCAAAACCCT
Downstream sequence
tccaagcaggaagaggaaggtcaaaggaccagtccagtctccatcccttttaaggagctttcctggaagttccacacaagttcttacaccccatcggcca
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.