Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019557
Fusion event
HBV-LYZ integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Host Sequence
Chromosome
chr12
Cytoband
q15
Reference genome
Start
End
69743887/69350107 (Hg38)
Location type
Exon2
Target gene
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-4668-5p ; hsa-mir-6720-5p ; hsa-mir-7703 ; hsa-mir-6512-3p ; hsa-mir-6729-5p ; hsa-mir-4649-5p ; hsa-mir-1273a ; hsa-mir-661 ; hsa-mir-873-3p ; hsa-mir-4486 ; hsa-mir-766-3p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-939-3p ; hsa-mir-6849-3p ; hsa-mir-3613-3p ; hsa-mir-508-5p ; hsa-mir-1247-3p ; hsa-mir-1273g-3p ; hsa-mir-3689d ; hsa-mir-377-5p ; hsa-mir-4252 ; hsa-mir-4537 ; hsa-mir-455-3p ; hsa-mir-4793-3p ; hsa-mir-5186 ; hsa-mir-6086 ; hsa-mir-6134 ; hsa-mir-6499-3p ; hsa-mir-6516-5p ; hsa-mir-6799-5p ; hsa-mir-6851-5p ; hsa-mir-6880-5p ; hsa-mir-7847-3p
Nearest miRNA
hsa-let-7i/Upstream/76889; hsa-mir-1178/Downstream/234615;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/109792, chr12-CpG: 57/Downstream/9618
Upstream sequence
ttggtctgGGCTCCCCTCCGGGCTGAGACAATATTTCTGAAAAGATGCAATGCAGAGCTCATACTCCCCCCACAAGGCTGCGGATCCTGCCTGGGCCTCA
Downstream sequence
ataactcatttctttctagaactaaatgagattccattgtccgaatataccacagtgatttgttcattcacccactgaaggatatcttggttgcttctaa
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.