SERPINA1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019559
Fusion event
HBV-SERPINA1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr14
Cytoband
q32.13
Reference genome
GRCh37/hg19
Start
94844978/94378641 (Hg38)
End
94844983/94378646 (Hg38)
Location type
Intron1
Target gene
SERPINA1
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-1249-5p ; hsa-mir-1343-3p ; hsa-mir-3529-5p ; hsa-mir-379-5p ; hsa-mir-4419a ; hsa-mir-4451 ; hsa-mir-4510 ; hsa-mir-4650-3p ; hsa-mir-4690-5p ; hsa-mir-6081 ; hsa-mir-6127 ; hsa-mir-6129 ; hsa-mir-6130 ; hsa-mir-6133 ; hsa-mir-6783-3p ; hsa-mir-6797-5p ; hsa-mir-6832-5p
Nearest miRNA
hsa-mir-1260a/Upstream/430339; hsa-mir-1185-1/Downstream/759273;
Nearest TSS
ENST00000550708/Upstream/55247; ENST00000536735/Downstream/4600;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/203330, chr14-CpG: 184/Downstream/389629
Upstream sequence
agttttgttttttccagaatgtcatgcatttggaatcatgtagtaggtaccttttttatattggcttttttcatttaacaatgtatatttaggctttttt
Downstream sequence
GGGAGAGAAGCAGAGACACGTTGTAAGGCTGATCCCAGGCCTCGAGCAAGGCTCACGTGGACACCTCCCAGGAAGCGCTCACTCCCCCTGGACGGCCCTG
Target sequence
TGGAG
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate