Fusion event
HBV-MYH13 integration
Detection method
VirusFinder
Disease
Hepatocellular carcinoma (HCC)
End
10269589/10366272 (Hg38)
Nearest miRNA
hsa-mir-1253/Upstream/2179136; hsa-mir-10226/Downstream/1715627;
Upstream sequence
TTCTCCAAATGCTTGACATACAAAAAGTCCCCAAAGAGGACCTGAGATTGCTGGTCCATTTCTTGGACTCTTAGTCTTATCTGATCTTGTGAGTTATTTT
Downstream sequence
ttttcCTTCCCACTTAATTCTATAACTGACATAAAATGGAGTCAAGTcatacacacacacacgcacacccacacataTCTCTCCATATCTCTCTTAAGAA
Target sequence
TTCCCGTAAGTCCTGTGTGGACTGTTCCTCTTCTCAGAATTTGcttctctcattccccctcggcacctcttccctctactccactacctattttcctcaagtctctttcctctttccttcccttctctcctc
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.