Basic Information
VIS ID
TVIS10019566
Fusion event
HBV-chr17 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr17
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
21743127/22216521 (Hg38)
End
21743651/22217045 (Hg38)
Nearest miRNA
hsa-mir-1180/Upstream/2871947; hsa-mir-10226/Downstream/5076865;
Nearest TSS
ENST00000595228/Upstream/523998; ENST00000578881/Downstream/49284;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/372058, chr17-CpG: 22/Downstream/224
Nearby gene
FAM27E5
Upstream sequence
CCCTGGTGTCCATGGCCCAGCATGGGCCGAGTGGGGAGGCCACGCCCTGGTCCCTGGTGCAGCTCCGGCCGTCCCTCCAACCCTTCCACTTGTCTGGCCT
Downstream sequence
aagcaaacaaacaaaaaaaaaaaccaagcatttggcaggcatggtagcgcacgcctgtggtcccagccagccactctggaggctgaggtgggaggatcgc
Target sequence
ctcagctcactgcaaactccgcctcccaggttcatgccattctccggcctcagcctcccaagtagctgggactacaggcgcccaccaccacgcccggctaatttttttgtatttttagtagagacgggggtttcaccgtgttagccaggatggtctcgatcttctgacttcgtgatccgcccgcctcagcctcccaaagtagtgggattacaggcgtgagccacagagcccagccGACGCCTTTTTTTTTCTTTC
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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