Fusion event
HBV-chr17 integration
Detection method
VirusFinder
Disease
Hepatocellular carcinoma (HCC)
End
21987709/22488380 (Hg38)
Nearest miRNA
hsa-mir-1180/Upstream/3143734; hsa-mir-10226/Downstream/4805530;
Upstream sequence
GTCAGGGCCAAGTTGGACCTGTGCTTACAATGACTCACGGGCCTTTTCCCCACCTGTCTACCCAACAGCCAACCCAGGAGTTAAACCCACAGCAGCCTCC
Downstream sequence
GTTAACTTCATGAAGATTATTAAAGTGATGAAAATATTTATCCTATTCTCTATAAAGCTCCAGCGAATATGGTTTTCTGCACATGCTTATCAAAGAATCT
Target sequence
TGTCCTCCTGCCACTGCATTGGTGCTGACTTCTAAAGGAGCAGCGGACGTGAAAAAGTTGACTTTCTTCTAG
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.