Basic Information
VIS ID
TVIS10019575
Fusion event
HBV-chr3 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr3
Cytoband
p21.2
Reference genome
GRCh37/hg19
Start
51904958/51870942 (Hg38)
End
51905047/51871031 (Hg38)
Nearest miRNA
hsa-mir-12127/Upstream/1195779; hsa-let-7g/Downstream/397247;
Nearest TSS
ENST00000440867/Upstream/9304; ENST00000440723/Downstream/2565;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/154897, chr3-CpG: 80/Downstream/70565
Nearby gene
IQCF5-AS1
Upstream sequence
TTACAGAATACAAAAGACTGTTTCTAGTTTACAATGCTGTGACTTCTCTTTCTACCACAGAATATGCTGGTTTATATGATGACATCTCCACTCAAGGCTG
Downstream sequence
cacctgtcctaaaatttatatggaatctaaagagaccccaaatagccaaaataatactgaaaaagaagagcaaatttggagatctcacacttccaaattt
Target sequence
gttggccaggctgatctcgaactcctgacctcaagtgatcctcctgccttggcctcccaaagtgctgagattacaggcatgagccacca
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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