Basic Information
VIS ID
TVIS10019576
Fusion event
HBV-chr3 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr3
Cytoband
p11.1
Reference genome
GRCh37/hg19
Start
89138029/89088879 (Hg38)
End
89138118/89088968 (Hg38)
Nearest miRNA
hsa-let-7g/Upstream/1862602; hsa-mir-12124/Downstream/7270996;
Nearest TSS
ENST00000440867/Upstream/750356; ENST00000452448/Downstream/18556;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/938516, chr3-CpG: 41/Downstream/25517
Nearby gene
EPHA3
Nearest cancer related gene
EPHA3(TSG, No orient)
Upstream sequence
TGACATTTTACATTTTGTACCTAATGTATGATATTTGGAGCAAAAAATTAGGTAGATAGAAATGGTCTTATTTAAATCATTGCTGCACTGGGTGGCAAAA
Downstream sequence
gatagataatagggtgactatggtttacaataatctgttgtatatttcaaaatgactacagggtcagatttggaatgttcccaacacaaagaaataatac
Target sequence
agctcagtagagcagtgaggacggggtatataaagggttggttaatgagcacaaacacagtttgataaaagaaataagacctagtgttt
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate