Basic Information
VIS ID
TVIS10019577
Fusion event
HBV-chr6 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr6
Cytoband
q16.1
Reference genome
GRCh37/hg19
Start
93683085/92973367 (Hg38)
End
93683174/92973456 (Hg38)
Fragile sites / regions
FRA6G
Nearest miRNA
hsa-mir-10398/Upstream/1451630; hsa-mir-1202/Downstream/5051075;
Nearest TSS
ENST00000381078/Upstream/249538; ENST00000452624/Downstream/96931;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/2361867, chr6-CpG: 92/Downstream/443098
Nearby gene
EPHA7
Upstream sequence
tgtatattgcaatcactagatccatcacttttaaaaagtatacaagaagatatagtttttttaaaaaacttaataagtaaattaaaatagaatacaaaaa
Downstream sequence
gatggcgggtgcctgtaacctcagtctgctcaggaggctgagggaggagaatagattgaacccaggaggtggaggttgcagtgagccaagatcgcgccac
Target sequence
Aggatcacttgaggtcaggagttcgagatcagcctgaccaacatggtgaaaccctatctctactaaaaatgcaaaaattagcggggcat
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate