Basic Information
VIS ID
TVIS10019581
Fusion event
HBV-SLC8B1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr12
Cytoband
q24.13
Reference genome
GRCh37/hg19
Start
113741800/113303995 (Hg38)
End
113741935/113304130 (Hg38)
Location type
Intron1
Fragile sites / regions
FRA12E ; FRA12D
Target gene
SLC8B1
Nearest miRNA
hsa-let-7i/Upstream/12387; hsa-mir-1178/Downstream/2844430;
Nearest TSS
ENST00000382841/Upstream/10976; ENST00000548997/Downstream/2714;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/82143, chr12-CpG: 34/Downstream/30698
Upstream sequence
TTATTTTACTTAGTTTTAAAAGAATGAGTGAGGAGGGCAATGCAGTTAGGAAAGAAAACATGAAAGGAATGCCTTGTCCTGCTCGGCTGGACCCTCAAGA
Downstream sequence
cagtctcccaaagtgctgggattacaggcatgagctaccacacccggccaagatgtcctagctcactcaaagtcatacagccagggacttaagtgatggg
Target sequence
tcagcctcccaagtagctgagattacaggtgtgcaccaccacacctgactaatttttgtatttttagtagagatggggtttcaccacgttggccaggctggtctcgaactcctgacctcaagtgatcctctgcct
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate