Fusion event
HBV-EVPLL integration
Detection method
VirusFinder
Disease
Hepatocellular carcinoma (HCC)
End
18287134/18383820 (Hg38)
Nearest miRNA
hsa-mir-1253/Upstream/42862; hsa-mir-10226/Downstream/960686;
Upstream sequence
ACCGGCAGCCACTTGTAGGGGTTGACGGTGACACAGAAGAGGCCTGAGTAGGTCTGGGAAGATCAGAACATTTATCATTTGGATCTCGTTTTTACTCAGA
Downstream sequence
aaattagctagaggtggtggcacgcgcctgtaatcccagctactcaggaggctgaggcaggagaatcgcttgaacccaggaggcggaggttgcagtgggc
Target sequence
gatcacttgaggtcaggagttcgagatcagcctggccaacatggtgaaaccctgtctctactaaaaatacca
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.