VISDB Viral Integration Site DataBase

VIS ID

TVIS10019592

Fusion event

HBV-CCNE1 integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Chromosome

chr19

Cytoband

q12

Reference genome

Start

End

30315953/29825046 (Hg38)

Location type

Intron11

Target gene

miRNAs that regulate target gene

hsa-mir-15b-5p ; hsa-mir-503-5p ; hsa-mir-424-5p ; hsa-mir-16-5p ; hsa-mir-15a-5p ; hsa-mir-107 ; hsa-mir-185-5p ; hsa-mir-103a-3p ; hsa-mir-26b-5p ; hsa-mir-26a-5p ; hsa-mir-16-1-3p ; hsa-mir-195-5p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-151a-3p ; hsa-mir-342-5p ; hsa-mir-125b-5p ; hsa-mir-92a-3p ; hsa-mir-383-3p ; hsa-mir-497-5p ; hsa-mir-4524a-5p ; hsa-mir-4694-3p ; hsa-mir-4524b-5p ; hsa-mir-6838-5p ; hsa-mir-7-5p ; hsa-mir-4477a ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-5191 ; hsa-mir-646 ; hsa-mir-25-5p ; hsa-mir-30c-2-3p ; hsa-mir-144-5p ; hsa-mir-892b

Nearest miRNA

hsa-mir-10395/Upstream/9424160; hsa-let-7e/Downstream/5297654;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/10740, chr19-CpG: 21/Downstream/18487

Nearest cancer related gene

CCNE1(OG, No orient, 0)

Upstream sequence

TCCCTCTTGGGTCTCTCTGGCTCATCCCCATCTCGCCCGCCCCATCCCAGCCCTTCTCCCCGCCTCCCACTGTGCGACACCCTCCCGCCCTCTCGGCCGC

Downstream sequence

TTTTTCCCCTTACCGAAATCTTAGCCTAAAGAATAAGTGAATTTTTATTTGGAGAACTTTTAACATAGTAGCCTAAAACTGCTTTTAAGAAGAAAATGAg

Target sequence

ctacagtctggatgagaaagcaagtctccatcttgagaaaaaaaaaaaatttaaaaattaaaaaagaaaAAGCCTATGGTAATTGAAGCCCAAGGATATGTTCTACTCTAATGTGTTGTCCCTTTTATTCTTACCAACAGGACAAAGCCCGAGCAAAGAAAGCCATGTTGTCTGAACAAAATAGGGCTTCTCCTCTCCCCAGTGGGCTCCTCACCCCGCCACAGAGCGGTAAGAAGCAGAGCAGCGGGCCGGAAA