Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019597
Fusion event
HBV-MREG integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1513
End
1725
Integrated sequence
ACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTT
Host Sequence
Chromosome
chr2
Cytoband
q35
Reference genome
End
216871068/216006345 (Hg38)
Location type
Intron4
Target gene
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-130b-3p ; hsa-mir-26b-5p ; hsa-mir-19b-3p ; hsa-mir-106a-3p ; hsa-mir-122-5p ; hsa-mir-1307-3p ; hsa-mir-130a-3p ; hsa-mir-144-5p ; hsa-mir-301a-3p ; hsa-mir-301b-3p ; hsa-mir-3135b ; hsa-mir-3652 ; hsa-mir-3666 ; hsa-mir-3925-5p ; hsa-mir-4295 ; hsa-mir-4430 ; hsa-mir-454-3p ; hsa-mir-4638-5p ; hsa-mir-4712-3p ; hsa-mir-488-5p ; hsa-mir-504-3p ; hsa-mir-589-5p ; hsa-mir-6812-3p ; hsa-mir-95-5p
Nearest miRNA
hsa-mir-10b/Upstream/2248186; hsa-mir-1244-1/Downstream/1894168;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/570208, chr2-CpG: 51/Downstream/6831
Upstream sequence
TTTATTAAATCATCTTATCACAAAGATGGAAACATATACAAACTAGAAACATGCAACCATCATCTTCCACAGTCAAGTCACAATGTCAAATATTTTTCTT
Downstream sequence
CTGGGACAGCACTCATGCACCTCTGGCCCTCCCCTATCACTCCCCTGTCTTTCAAGAAGGCAAAAGCACCAGCCTTGCAATGGGAATCTTCCAGCCAGGG
Reference
Cancer Genome Atlas Research Network. Electronic address, w. b. e. and N. Cancer Genome Atlas Research . Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma. Cell ,2017,169(7): 1327-1341 e13