Basic Information
VIS ID
TVIS10019611
Fusion event
HBV-chr1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28622513
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1365
End
1621
Integrated sequence
CATCGTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTTTACGTCCCGTCGGCGCTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCAC
Host Sequence
Chromosome
chr1
Cytoband
p36.12
Reference genome
GRCh37/hg19
Start
23012373/22685880 (Hg38)
End
23012373/22685880 (Hg38)
Fragile sites / regions
FRA1A
Nearest miRNA
hsa-mir-12136/Upstream/52514; hsa-mir-101-1/Downstream/33637;
Nearest TSS
ENST00000473358/Upstream/32691; ENST00000490436/Downstream/24959;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/8542, chr1-CpG: 162/Downstream/24450
Nearby gene
EPHB2
Nearest cancer related gene
EPHB2(TSG, No orient)
Upstream sequence
TCTCCACTTTTAGCCAAGTAAAAGAGGTTTTTGTTTTTTGTTTGTTTGTTTTCCCCAAAGGAACTAAATCTACCTTTCTCTTAAAATATCAGGCTTGTGT
Downstream sequence
TCCAAGGGAAGAATGAGGTCTTCATTTTTCTATCACCAGTACCTACAAGTGTACCTAGCATAAAGAGTAAGGTGGTTTTTAAAACTGGTATATAATAATT
Reference
Cancer Genome Atlas Research Network. Electronic address, w. b. e. and N. Cancer Genome Atlas Research . Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma. Cell ,2017,169(7): 1327-1341 e13
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