FRZB _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019621
Fusion event
HBV-FRZB integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28622513
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
457
Integrated sequence
ACTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATC| |AAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAAGGAACCTCTATGTA
Host Sequence
Chromosome
chr2
Cytoband
q32.1
Reference genome
GRCh37/hg19
Start
183707272/182842544 (Hg38)
End
183707272/182842544 (Hg38)
Location type
Intron4
Fragile sites / regions
FRA2G
Target gene
FRZB
miRNAs that regulate target gene
hsa-mir-30b-5p ; hsa-mir-744-5p ; hsa-mir-451a ; hsa-mir-125b-1-3p
Nearest miRNA
hsa-mir-10b/Upstream/1536892; hsa-mir-1244-1/Downstream/1536431;
Nearest TSS
ENST00000437798/Upstream/112696; ENST00000342619/Downstream/24618;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/126069, chr2-CpG: 38/Downstream/23536
Upstream sequence
tcgggaggctgaggcaggagaatggcgtgaacccgggaggcagagcttgcagtgagcagagatcgcaccactgcactccagcctgggtgacagagcaaga
Downstream sequence
TGAAAAACACATTTTAGTTATAAGCACATTTCCAATATTAGCTTTCTTTTGTTTTGCTCAGACTCACATTTTTTGCTCAGACTAGATCTCAATTTGGTGG
Reference
Cancer Genome Atlas Research Network. Electronic address, w. b. e. and N. Cancer Genome Atlas Research . Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma. Cell ,2017,169(7): 1327-1341 e13
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