VISDB Viral Integration Site DataBase

VIS ID

TVIS10019628

Fusion event

HBV-KCNAB1 integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Start

1377

End

1727

Integrated sequence

GGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTTTACGTCCCGTCGGCGCTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCA

Chromosome

chr3

Cytoband

q25.31

Reference genome

Start

End

156016801/156299012 (Hg38)

Location type

Intron1

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-578 ; hsa-mir-526b-5p ; hsa-mir-144-5p ; hsa-mir-3613-3p ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-4282 ; hsa-mir-3606-3p

Nearest miRNA

hsa-let-7g/Upstream/4733017; hsa-mir-1224/Downstream/2983634;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/7481, chr3-CpG: 49/Downstream/255835

Upstream sequence

tagttaaaatacaaatgtagcagcattagaatttagagtttatctgaggagactcgatttattttgcaacaccagattgcatgtggtatggggatttcct

Downstream sequence

AACTCAAGACGCCATCTAGTACAGTTACTTTGTTTTATATAGATTGGCCAGTTAGTTCCTTGGTCAGAGTTACCCATGAAGTTGGGCAGAGGGCCAAGGC