VISDB Viral Integration Site DataBase

VIS ID

TVIS10019648

Fusion event

HBV-TRDN integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Start

1569

End

1795

Integrated sequence

TGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAAT

Chromosome

chr6

Cytoband

q22.31

Reference genome

Start

End

123611548/123290403 (Hg38)

Location type

Intron17

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-148b-3p ; hsa-mir-335-3p ; hsa-mir-1305 ; hsa-mir-498 ; hsa-mir-561-5p ; hsa-mir-4761-5p ; hsa-mir-3974 ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p ; hsa-mir-491-3p ; hsa-mir-7703 ; hsa-mir-6845-3p ; hsa-mir-4639-3p ; hsa-mir-502-3p ; hsa-mir-501-3p

Nearest miRNA

hsa-mir-10398/Upstream/3275146; hsa-mir-1202/Downstream/3194228;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/293795, chr6-CpG: 98/Downstream/512629

Upstream sequence

AAGTTGCCCTTAGTTTTCCTGCCTTGTCAGGAGTCTCAGGCACAGTCATGAAAGTTGTTGATCTTTGCCTTTTCTTTTCCACATGGTTAGGTGATGTACA

Downstream sequence

taaataagactagtcaaagcttactagtttgaagagaatattatgtcttctaaaatttaacagaatttttatctaagtaaatcactgatgttcattggct