Basic Information
VIS ID
TVIS10019666
Fusion event
HBV-chr12 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28622513
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1579
End
1803
Integrated sequence
TGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGC
Host Sequence
Chromosome
chr12
Cytoband
q24.31
Reference genome
GRCh37/hg19
Start
123757297/123272750 (Hg38)
End
123757297/123272750 (Hg38)
Fragile sites / regions
FRA12E
Nearest miRNA
hsa-let-7i/Upstream/262022; hsa-mir-3612/Downstream/92014;
Nearest TSS
ENST00000382841/Upstream/416; ENST00000602918/Downstream/77691;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/642, chr12-CpG: 124/Downstream/91320
Nearby gene
CDK2AP1
Nearest cancer related gene
CDK2AP1(TSG, No orient)
Upstream sequence
TCTGTTACGGTCCAGGGCAAGGTCTTTGAAAGGTGTGAGTTGGCCAGAACTCTGAAAAGATTGGGAATGGATGGCTACAGGGGAATCAGCCTAGCAAACT
Downstream sequence
CCAGTTAACAAATGCGAGCATCCAGTACCGTGCCCATGACTGTGGGTGCAGGGAGCAGAGTGTAGGCAGATGAGCAAATGGGGTTTCCATGCCTGAGGAA
Reference
Cancer Genome Atlas Research Network. Electronic address, w. b. e. and N. Cancer Genome Atlas Research . Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma. Cell ,2017,169(7): 1327-1341 e13
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