WWOX _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019673
Fusion event
HBV-WWOX integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
28622513
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1441
End
1826
Integrated sequence
GCTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGAC
Host Sequence
Chromosome
chr16
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
79162744/79128847 (Hg38)
End
79162996/79129099 (Hg38)
Location type
Intron8
Target gene
WWOX
Nearest miRNA
hsa-mir-1225/Upstream/2259828; hsa-mir-11401/Downstream/2255919;
Nearest TSS
ENST00000527434/Upstream/50613; ENST00000566103/Downstream/67260;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/1028678, chr16-CpG: 44/Downstream/460495
Nearest cancer related gene
WWOX(TSG, No orient, 0)
Upstream sequence
GACTCATCGTTTGTGTTTGTCAATTTGCAGTTCAGCTTAGCCCTTCCCTGTTCCTGTGTAGTTACAATCTGGCCCTGAAGACATCCGAGGCACTTCAGTA
Downstream sequence
AATGCTTGCAAACAACGGTAGTTATAAAATGTTGCCTCCTGTATCTCAGTAGGCACTGTTCAAGCATTTGAACTTCATCAAGTATCAAGACAAGTCTAAG
Target sequence
TGAAGGTTGTGATTCAGTTGCCCAAGCAGTAAGGCCTGACTGGTGTCACGATCCCACAACCCGCACAAAGGTGCCATTGTTGCCCAGTGTGAAGGGAGCTGAGGCATCACCAAAGGGGGCCAAGCGTCCCTTCTCTGGGTTAGAAATGTTGTTTTCCATTTGCTGGTAAACAACAGTCCAAGTTCATTGTCCTGACACAGAACTCTGTTTCTTCTTTTATGCTGAGAGTTTGCAAGTATGGATCTTGATAGG
Reference
Cancer Genome Atlas Research Network. Electronic address, w. b. e. and N. Cancer Genome Atlas Research . Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma. Cell ,2017,169(7): 1327-1341 e13
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