VISDB Viral Integration Site DataBase

VIS ID

TVIS10019675

Fusion event

HBV-ZNF331 integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Start

1393

End

1758

Integrated sequence

TGCCAACTGGATCCTGCGCGGGACGTCCTTTGTTTACGTCCCGTCGGCGCTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAG

Chromosome

chr19

Cytoband

q13.42

Reference genome

Start

End

54071260/53568006 (Hg38)

Location type

Intron3

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-20a-5p ; hsa-mir-4474-3p ; hsa-mir-7108-5p ; hsa-mir-664b-3p ; hsa-mir-579-3p ; hsa-mir-6815-3p ; hsa-mir-5696 ; hsa-mir-6828-5p ; hsa-mir-4729 ; hsa-mir-6510-3p ; hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-31-5p ; hsa-mir-661 ; hsa-mir-873-3p ; hsa-mir-6860 ; hsa-mir-612 ; hsa-mir-5189-5p ; hsa-mir-3187-5p ; hsa-mir-1285-3p ; hsa-mir-766-3p ; hsa-mir-939-3p ; hsa-mir-6849-3p ; hsa-mir-5586-3p ; hsa-mir-508-5p

Nearest miRNA

hsa-let-7e/Upstream/1286113; hsa-mir-10394/Downstream/98673;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/13006, chr19-CpG: 86/Downstream/79816

Upstream sequence

CCCCAGCACCGCCACGGGAGGCCCTCCGGAAGACAGTCCCACCGTGGCCCCCAAAAGCACCACCTTCCTGAAGAATATCCGGCAGTTTATTATGCCTGTG

Downstream sequence

ttgggaggacaaggagggcagatcacgaggtcgggagtttgagaccagcctggccaacatggtgaaaccccatctctactaaaaatacaaaaattagctg