Basic Information
VIS ID
TVIS10019690
Fusion event
HBV-chr18 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28622513
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1823
Integrated sequence
TTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACT| |TTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAA
Host Sequence
Chromosome
chr18
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
65970394/68303157 (Hg38)
End
65970394/68303157 (Hg38)
Fragile sites / regions
FRA18C
Nearest miRNA
hsa-mir-1-2/Upstream/1221471; hsa-mir-548av/Downstream/4550164;
Nearest TSS
ENST00000575820/Upstream/38330; ENST00000577835/Downstream/123873;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/786421, chr18-CpG: 67/Downstream/411540
Nearby gene
TMX3
Upstream sequence
AATGATTATGATAAAAATAAATCATTTTATTCAAGCTATTGTCATAATACAATGCATACATGAAAACAGAACCCAATAAGTAAACTCGGCCACCGGCCAT
Downstream sequence
CTTGAGATTACTGGAATGTTGTTTATTTTATGATAGTGAGAGAGCTAAGCcaaaactgcacaactacatggaaactgaacaacctgctcctgaatgacta
Reference
Cancer Genome Atlas Research Network. Electronic address, w. b. e. and N. Cancer Genome Atlas Research . Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma. Cell ,2017,169(7): 1327-1341 e13
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