CHL1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019706
Fusion event
HBV-CHL1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28622513
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1826
Integrated sequence
AAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTT| |TCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAA
Host Sequence
Chromosome
chr3
Cytoband
p26.3
Reference genome
GRCh37/hg19
Start
440739/399056 (Hg38)
End
440739/399056 (Hg38)
Location type
Exon26
Target gene
CHL1
miRNAs that regulate target gene
hsa-mir-10a-5p ; hsa-mir-335-5p ; hsa-mir-132-3p ; hsa-mir-181a-5p ; hsa-mir-590-5p ; hsa-mir-182-5p
Nearest miRNA
hsa-let-7g/Downstream/4851121;
Nearest TSS
ENST00000440867/Upstream/9611; ENST00000442809/Downstream/137175;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/89846, chr3-CpG: 182/Downstream/1699289
Nearest cancer related gene
CHL1(OG, No orient, 0)
Upstream sequence
cactctgtcgcccaggctggagtgcagtggcgtgatctctgctcactgcaagctccgcctcctgggttcacaccattctcctgcctcagcctcctgagta
Downstream sequence
GTTTATTGGACTGATGTGTGCGATTGCTCTTCTCACACTACTATTATTAACTGTTTGCTTTGTGAAGAGGAATAGAGGTGGAAAGTACTCAGGTAAAATT
Reference
Cancer Genome Atlas Research Network. Electronic address, w. b. e. and N. Cancer Genome Atlas Research . Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma. Cell ,2017,169(7): 1327-1341 e13
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