Basic Information
VIS ID
TVIS10019714
Fusion event
HBV-NOCT integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28622513
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1770
Integrated sequence
GACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTT| |TGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAG
Host Sequence
Chromosome
chr4
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
139949590/139028436 (Hg38)
End
139949590/139028436 (Hg38)
Location type
Intron1
Target gene
NOCT
miRNAs that regulate target gene
hsa-mir-296-3p ; hsa-let-7e-5p
Nearest miRNA
hsa-mir-12113/Upstream/13521129; hsa-mir-1305/Downstream/4315024;
Nearest TSS
ENST00000502981/Upstream/12640; ENST00000515616/Downstream/14636;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/12162, chr4-CpG: 18/Downstream/54478
Upstream sequence
ttgtaaaAATTCTCACAGAATTTTTTTTATGTTTGTTGAATATGAAAGTATGATAATTACTTTTGTTGAGCAACTATCAGCATAGCAGATGTTTGAACTG
Downstream sequence
TTGATATCTCTGGTAATGCCAAGCGGGTCGTGGCACTGCTTTGTACACTCTGTGCTGTGGCAGTGTGTGTGTGCTGTGACGACAGTGACGTCGACAGATG
Reference
Cancer Genome Atlas Research Network. Electronic address, w. b. e. and N. Cancer Genome Atlas Research . Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma. Cell ,2017,169(7): 1327-1341 e13
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