VISDB Viral Integration Site DataBase

VIS ID

TVIS10019723

Fusion event

HBV-ESR1 integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Start

1261

End

1731

Integrated sequence

GCCGATCCATACTGCGGAACTCCTAGCCGCTTGTTTTGCTCGCAGCAGGTCTGGAGCAAACATTATCGGGACTGATAACTCTGTTGTCCTATCCCGCAAATATACATCGTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTTTACGTCCCGTCGGCGCTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACC

Chromosome

chr6

Cytoband

q25.1

Reference genome

Start

End

152063866/151742731 (Hg38)

Location type

Intron2

Target gene

miRNAs that regulate target gene

hsa-mir-302c-3p ; hsa-mir-206 ; hsa-mir-193b-3p ; hsa-mir-18b-5p ; hsa-mir-18a-5p ; hsa-mir-22-3p ; hsa-mir-19a-3p ; hsa-mir-29b-3p ; hsa-mir-19b-3p ; hsa-mir-20b-5p ; hsa-mir-221-3p ; hsa-mir-222-3p ; hsa-mir-130a-3p ; hsa-mir-26a-5p ; hsa-mir-145-5p ; hsa-mir-3668 ; hsa-mir-4671-3p ; hsa-mir-4709-3p ; hsa-mir-7852-3p ; hsa-mir-100-5p ; hsa-mir-142-3p ; hsa-mir-6073 ; hsa-mir-6757-3p ; hsa-mir-4422 ; hsa-mir-548e-5p ; hsa-mir-454-3p ; hsa-mir-130b-3p ; hsa-mir-301a-3p ; hsa-mir-301b-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-129-5p ; hsa-mir-874-3p ; hsa-mir-3157-3p ; hsa-mir-4290 ; hsa-mir-5582-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-5589-3p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-7855-5p ; hsa-mir-9-5p ; hsa-mir-4264 ; hsa-mir-4797-3p ; hsa-mir-3121-5p ; hsa-mir-1910-5p ; hsa-mir-26b-3p ; hsa-mir-192-5p ; hsa-mir-335-3p

Nearest miRNA

hsa-mir-10398/Upstream/639955; hsa-mir-1202/Downstream/3110629;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/248339, chr6-CpG: 105/Downstream/64956

Nearest cancer related gene

ESR1(TSG, No orient, 0)

Upstream sequence

aggcacgttcagggtggtatggccatagacCCCAACTTCAAAACAACAGGCACATCCATTCAATTCAGGTAGCACCCACCAACTGTACcatgggcttaag

Downstream sequence

GCAATTTATTGAGTGACAGtgtgtgttttattcattgatcgtcattacacttagaatagggtcggggatatagcaggcattcaatcaatatttttgaggg