Basic Information
VIS ID
TVIS10019729
Fusion event
HBV-ERCC6L2 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28622513
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1749
Integrated sequence
TCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGA| |GGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTT
Host Sequence
Chromosome
chr9
Cytoband
q22.32
Reference genome
GRCh37/hg19
Start
98665857/95903575 (Hg38)
End
98665857/95903575 (Hg38)
Location type
Intron3
Target gene
ERCC6L2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-3162-3p ; hsa-mir-6771-3p ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-7977 ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-7154-3p ; hsa-mir-5004-5p ; hsa-mir-383-3p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-3714 ; hsa-mir-122-3p ; hsa-mir-1915-3p ; hsa-mir-1976 ; hsa-mir-2276-3p ; hsa-mir-3194-3p ; hsa-mir-3653-5p ; hsa-mir-4279 ; hsa-mir-4722-3p ; hsa-mir-4726-3p ; hsa-mir-5001-3p ; hsa-mir-6727-3p ; hsa-mir-6747-3p ; hsa-mir-6764-5p ; hsa-mir-6778-3p ; hsa-mir-6791-3p ; hsa-mir-6796-3p ; hsa-mir-6829-3p ; hsa-mir-6836-3p ; hsa-mir-6840-3p ; hsa-mir-6890-3p
Nearest miRNA
hsa-let-7a-1/Upstream/817481; hsa-mir-12126/Downstream/1459979;
Nearest TSS
ENST00000422679/Upstream/27432; ENST00000426805/Downstream/12226;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/27412, chr9-CpG: 122/Downstream/117359
Upstream sequence
acacaacaaaaaattagacaaacatggtggcgtgggcctttagtcccagctactcaggaggctgaggcgagcagatgacttgagcctagaattttaaggc
Downstream sequence
CCTGGGTCTCTTTACGTCACAGCAAGCGCTTGTTAGCTGATTAACAATTAGCCATGGCCATGAGTTCATAGGCTCACCCCAAGGACTGGGCACCCCCTCC
Reference
Cancer Genome Atlas Research Network. Electronic address, w. b. e. and N. Cancer Genome Atlas Research . Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma. Cell ,2017,169(7): 1327-1341 e13
Curate