VISDB Viral Integration Site DataBase

VIS ID

TVIS10019734

Fusion event

HBV-ARID5B integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Start

1540

End

1814

Integrated sequence

CGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAA

Chromosome

chr10

Cytoband

q21.2

Reference genome

Start

End

63844393/62084634 (Hg38)

Location type

Intron8

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-128-3p ; hsa-mir-101-3p ; hsa-mir-22-3p ; hsa-mir-196a-5p ; hsa-mir-196b-5p ; hsa-mir-1277-5p ; hsa-mir-3653-3p ; hsa-mir-3658 ; hsa-mir-5011-5p ; hsa-mir-186-3p ; hsa-mir-320a ; hsa-mir-373-5p ; hsa-mir-576-3p ; hsa-mir-616-5p ; hsa-mir-767-3p ; hsa-mir-320b ; hsa-mir-320c ; hsa-mir-320d ; hsa-mir-4426 ; hsa-mir-4429 ; hsa-mir-4491 ; hsa-mir-4647 ; hsa-mir-4657 ; hsa-mir-4662b ; hsa-mir-371b-5p ; hsa-mir-6833-5p ; hsa-mir-570-5p ; hsa-mir-3692-3p ; hsa-mir-548ag ; hsa-mir-548ai ; hsa-mir-4476 ; hsa-mir-4694-3p ; hsa-mir-5692a ; hsa-mir-6876-5p ; hsa-mir-548ba ; hsa-mir-33a-5p ; hsa-mir-185-5p ; hsa-mir-432-5p ; hsa-mir-33b-5p ; hsa-mir-1284 ; hsa-mir-4306 ; hsa-mir-4644 ; hsa-mir-5192 ; hsa-mir-6813-3p ; hsa-mir-583 ; hsa-mir-573 ; hsa-mir-3156-5p ; hsa-mir-3616-5p ; hsa-mir-4670-3p ; hsa-mir-190a-3p ; hsa-mir-656-3p ; hsa-mir-4795-3p ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-3190-3p ; hsa-mir-7856-5p ; hsa-mir-552-3p ; hsa-mir-127-5p ; hsa-mir-7843-3p ; hsa-mir-140-3p ; hsa-mir-4482-3p ; hsa-mir-152-5p ; hsa-mir-597-3p ; hsa-mir-182-3p ; hsa-mir-4680-5p ; hsa-mir-126-5p ; hsa-mir-218-2-3p ; hsa-mir-3928-3p ; hsa-mir-620 ; hsa-mir-1270 ; hsa-mir-4531 ; hsa-mir-324-5p ; hsa-mir-423-5p ; hsa-mir-3184-5p ; hsa-mir-6866-3p ; hsa-mir-188-5p ; hsa-mir-6743-5p ; hsa-mir-4688

Nearest miRNA

hsa-mir-1265/Upstream/4780075; hsa-mir-107/Downstream/1288323;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/181094, chr10-CpG: 67/Downstream/183648

Upstream sequence

tgatttaattgtttgaggctagactggacatagggagttttaaaggatccccacgaggctgttaagggcatcgcagttaaagaaccactgATCTAAAGAG

Downstream sequence

ATATAAAGAATGATCAGCATTATACATTAATATTACTAACAACAACTCCTGTATATCTTGGACTCCTCCTCCATTTCTACTGTAATGcaatggttctcaa