VISDB Viral Integration Site DataBase

VIS ID

TVIS10019745

Fusion event

HBV-OAZ2 integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Start

1579

End

1841

Integrated sequence

TGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCT

Chromosome

chr15

Cytoband

q22.31

Reference genome

Start

End

64992407/64700208 (Hg38)

Location type

Intron4

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-26b-5p ; hsa-mir-222-3p ; hsa-mir-6814-5p ; hsa-mir-1228-3p ; hsa-mir-2355-5p ; hsa-mir-711

Nearest miRNA

hsa-mir-10393/Upstream/829189; hsa-mir-11181/Downstream/62179;

Nearest TSS

Nearest CpG islands

None/Target, chr15-CpG: 55/Upstream/239130, chr15-CpG: 42/Downstream/2795

Upstream sequence

CTCAGATACCTAGCACCTACTGCAGGCTGAGGAGAGAGTGGAAGGAAGAAGCAGGTCCCCCTAGTGTGGACTGGGCTGAGATCGGGTCATCTGCTGAACT

Downstream sequence

agaattttcgagtcaagttaacccaaccccctcttcttttcacatgtaagcacactggctcagccagaactcaggtctttcaacctcacaGTTGGTGAAG