Basic Information
VIS ID
TVIS10019751
Fusion event
HBV-SYNDIG1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
28622513
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1404
End
1754
Integrated sequence
TCCTGCGCGGGACGTCCTTTGTTTACGTCCCGTCGGCGCTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAA
Host Sequence
Chromosome
chr20
Cytoband
p11.21
Reference genome
GRCh37/hg19
Start
24471085/24490449 (Hg38)
End
24471102/24490466 (Hg38)
Location type
Intron1
Target gene
SYNDIG1
miRNAs that regulate target gene
hsa-mir-17-5p
Nearest miRNA
hsa-mir-103a-2/Upstream/6019758; hsa-mir-1-1/Downstream/1717720;
Nearest TSS
ENST00000382410/Upstream/21250; ENST00000482637/Downstream/11879;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/19048, chr20-CpG: 18/Downstream/427852
Upstream sequence
TTCTCTAGCTTTCAAGTGTCTGCTACTTAGTCCATCTGTTGTTCTATTATGTTGTGTTTGGCAAACAGATGCAGGAGAAGAACACTATTGCCTTTTCTGT
Downstream sequence
GGCATAAAGAAGGTTGTATCTGgggctctgctgccaatgtgcccgggcttggaccctggctcgcccctagcccttgggagatcattcaacctctctgtgc
Target sequence
GGCAGTGGAAGGGGCTA
Reference
Cancer Genome Atlas Research Network. Electronic address, w. b. e. and N. Cancer Genome Atlas Research . Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma. Cell ,2017,169(7): 1327-1341 e13
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