CLDN10 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019763
Fusion event
HBV-CLDN10 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28622513
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
2448
Integrated sequence
TAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAA| |TGTTAGTATTCCTTGGACTCATAAGGTGGGGAACTTTACTGGGCTTTATTCTTCTACTGTACCTGTCTTTAATCCTCATTGGAAAACACCATCTTTTCCT
Host Sequence
Chromosome
chr13
Cytoband
q32.1
Reference genome
GRCh37/hg19
Start
96229484/95577230 (Hg38)
End
96229484/95577230 (Hg38)
Location type
Exon4
Fragile sites / regions
FRA13D
Target gene
CLDN10
miRNAs that regulate target gene
hsa-mir-331-3p ; hsa-mir-6810-3p ; hsa-mir-6801-3p ; hsa-mir-6729-3p ; hsa-mir-4756-3p ; hsa-mir-3919 ; hsa-mir-3925-5p ; hsa-mir-486-5p
Nearest miRNA
hsa-mir-1297/Upstream/3087010; hsa-mir-1267/Downstream/849999;
Nearest TSS
ENST00000623511/Upstream/17080; ENST00000376795/Downstream/10444;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/23988, chr13-CpG: 89/Downstream/64122
Upstream sequence
TTGAGGTCAGAAAACGTCTATGCAACTGTATCTTCTTTCCCTAGCACAGTACCTAGAAGTGAAATTCTTATGTGTAGACCTAGTCCTTTCAGAATTAGCA
Downstream sequence
AAGAAAATTGTTGTCTCAGTGGATAGAGGGAGCCTCCCAGAGGATGGAGCAAGAAAGCTCTCTTCTTCCCATTATTATCTTACATTAATCTTACAAAAAC
Reference
Cancer Genome Atlas Research Network. Electronic address, w. b. e. and N. Cancer Genome Atlas Research . Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma. Cell ,2017,169(7): 1327-1341 e13
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