Basic Information
VIS ID
TVIS10019764
Fusion event
HBV-PROSER3 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28622513
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
336
Integrated sequence
AATACCGCAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAACTACCGTGTGTCTTGGCCAAAATTCGCAGTCCCCAACCTCCAATCAC| |TCACCAACCTCTTGTCCTCCAACTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCT
Host Sequence
Chromosome
chr19
Cytoband
q13.12
Reference genome
GRCh37/hg19
Start
36255836/35764935 (Hg38)
End
36255836/35764935 (Hg38)
Location type
Exon6
Fragile sites / regions
FRA19A
Target gene
PROSER3
miRNAs that regulate target gene
hsa-mir-331-3p ; hsa-mir-196a-5p ; hsa-mir-1202 ; hsa-mir-128-3p ; hsa-mir-185-3p ; hsa-mir-216a-3p ; hsa-mir-221-5p ; hsa-mir-3150a-5p ; hsa-mir-3150b-5p ; hsa-mir-3613-3p ; hsa-mir-3614-3p ; hsa-mir-3681-3p ; hsa-mir-3972 ; hsa-mir-4258 ; hsa-mir-4283 ; hsa-mir-4297 ; hsa-mir-4438 ; hsa-mir-4489 ; hsa-mir-4684-5p ; hsa-mir-4707-3p ; hsa-mir-4731-5p ; hsa-mir-4755-3p ; hsa-mir-4793-5p ; hsa-mir-4794 ; hsa-mir-5006-5p ; hsa-mir-5095 ; hsa-mir-548c-3p ; hsa-mir-548v ; hsa-mir-5581-5p ; hsa-mir-6502-3p ; hsa-mir-664a-5p ; hsa-mir-6789-3p ; hsa-mir-7151-3p ; hsa-mir-8073
Nearest miRNA
hsa-mir-10395/Upstream/419308; hsa-let-7e/Downstream/3644688;
Nearest TSS
ENST00000633603/Upstream/5050; ENST00000542591/Downstream/167;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/6529, chr19-CpG: 58/Downstream/10397
Upstream sequence
attctccacctgcccagcacagtgggcgagagtggacggtggtgctcccttggcaaactggagaggcctcaggatcccgcctcagccagccagcgcatca
Downstream sequence
GGTGCCCGCACCCCTGCCCCCATCACCCTTCCTACTGCGGCTCCACGTGGCCCAGGTCTCGAGACCTCCATTGCCTCACTCCTGCCTTCTCCCTGCAGCA
Reference
Cancer Genome Atlas Research Network. Electronic address, w. b. e. and N. Cancer Genome Atlas Research . Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma. Cell ,2017,169(7): 1327-1341 e13
Curate