Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019767
Fusion event
HBV-MEIS1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1814
Integrated sequence
GACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCAC| |CATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGAC
Host Sequence
Chromosome
chr2
Cytoband
p14
Reference genome
Start
End
66724603/66497471 (Hg38)
Location type
Intron7
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-204-5p ; hsa-mir-155-5p ; hsa-mir-98-5p ; hsa-let-7a-5p ; hsa-mir-495-3p ; hsa-mir-101-3p ; hsa-mir-21-5p ; hsa-mir-484 ; hsa-mir-196b-5p ; hsa-mir-4311 ; hsa-mir-1286 ; hsa-mir-3667-3p ; hsa-mir-4421 ; hsa-mir-4668-3p ; hsa-mir-4722-5p ; hsa-mir-4780 ; hsa-mir-548c-3p ; hsa-mir-5699-3p ; hsa-mir-623 ; hsa-mir-6511b-5p ; hsa-mir-6748-3p ; hsa-mir-6780b-3p ; hsa-mir-6811-5p ; hsa-mir-6841-3p ; hsa-mir-7152-5p ; hsa-mir-873-5p
Nearest miRNA
hsa-mir-1301/Upstream/139143; hsa-mir-10b/Downstream/2606211;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/50967, chr2-CpG: 129/Downstream/78287
Nearest cancer related gene
MEIS1(OG, No orient, 0)
Upstream sequence
tggatagacacctctttcacatctgggctattgtgaataatgctgcaatgaacatagaagtgccaatgtaccttccagactctgatttcagttctcttga
Downstream sequence
CTAGAGAAGAGATGGAAAGTTAGTCCTGTTTTTCGGTAGTGTGTCTCACTTTTCCTGGATCTGAAAGATACTTTCTTAAATGATATAACTTTTTTCCTTA
Reference
Cancer Genome Atlas Research Network. Electronic address, w. b. e. and N. Cancer Genome Atlas Research . Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma. Cell ,2017,169(7): 1327-1341 e13