Basic Information
VIS ID
TVIS10019778
Fusion event
HBV-chr1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1824
Integrated sequence
TTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTT| |TTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAG
Host Sequence
Chromosome
chr1
Cytoband
p22.2
Reference genome
GRCh37.55
Start
88547959/88082276 (Hg38)
End
88547959/88082276 (Hg38)
Fragile sites / regions
FRA1D
Nearest miRNA
hsa-mir-101-1/Upstream/1724589; hsa-mir-11399/Downstream/5764556;
Nearest TSS
ENST00000473358/Upstream/88999; ENST00000436111/Downstream/146021;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/746727, chr1-CpG: 63/Downstream/380324
Nearby gene
PKN2-AS1
Upstream sequence
AATACtatacatacatattatgcatatgtatctgtgtacattttgtatatatgtatgtatatataatttcatttgattatcatagcaaacttgtaggtgc
Downstream sequence
ttttctttgcagatgaagataatagcagagaagttagatcatttgcccatcacattgttcagtaTATAGTGAACATGTATTAACATTTGTGGTATGAATG
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate