Basic Information
VIS ID
TVIS10019787
Fusion event
HBV-chr11 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1735
Integrated sequence
AATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGG| |GAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTG
Host Sequence
Chromosome
chr11
Cytoband
q13.3
Reference genome
GRCh37.55
Start
69151755/69336987 (Hg38)
End
69151755/69336987 (Hg38)
Fragile sites / regions
FRA11H ; FRA11A
Nearest miRNA
hsa-mir-10392/Upstream/253729; hsa-let-7a-2/Downstream/946968;
Nearest TSS
ENST00000527297/Upstream/20155; ENST00000540356/Downstream/373;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/179498, chr11-CpG: 26/Downstream/40072
Nearby gene
LOC102724265
Upstream sequence
ccaggatgcagaggttgcagtgagccaaaaAAAAAAAAAAAAGAATAATAATAGCTACAATACTTTATTAAGGTATATACAATATAAAAAGATGCAAATT
Downstream sequence
CTAGTCATTAAGATGTTCACAAATCCTTTATCTACATGAAGTTTGGGAGAGATGTTATCTTTAATCCATTTATATATGGTTTGAGGGGATGGATCCAACT
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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