Basic Information
VIS ID
TVIS10019788
Fusion event
HBV-LOC107984456 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1812
Integrated sequence
AAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGC| |ACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCG
Host Sequence
Chromosome
chr12
Cytoband
q24.33
Reference genome
GRCh37.55
Start
132674929/132190384 (Hg38)
End
132674929/132190384 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA12E
Target gene
LOC107984456
Nearest miRNA
hsa-let-7i/Upstream/3896206; hsa-mir-6763/Downstream/391613;
Nearest TSS
ENST00000382841/Upstream/171; ENST00000543317/Downstream/15408;
Nearest CpG islands
chr12-CpG: 129/Target, None/Upstream, None/Downstream
Nearby gene
GALNT9
Upstream sequence
atcacgaatggctattaaatatataaaaagatgctcaaattaattgataatgacaggattgcaattaaaacTCACCCAAATTGTCAACCATCAAAAATGT
Downstream sequence
TGCAGATTTAATTAGACACAGGCGTGCAAGCATCATCTCCGGATCTGATGACAAAGGCACCCACCTAGGGATGCCCACCCAGGCCTGCTTCTTCCTTTAG
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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