Basic Information
VIS ID
TVIS10019789
Fusion event
HBV-chr13 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1796
Integrated sequence
CTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAAT| |TGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTT
Host Sequence
Chromosome
chr13
Cytoband
q13.3
Reference genome
GRCh37.55
Start
35487757/34913620 (Hg38)
End
35487757/34913620 (Hg38)
Fragile sites / regions
FRA13A
Nearest miRNA
hsa-mir-2276/Upstream/10751116; hsa-mir-1267/Downstream/4750414;
Nearest TSS
ENST00000623511/Upstream/242438; ENST00000497540/Downstream/14456;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/1095264, chr13-CpG: 79/Downstream/28614
Nearby gene
NBEA
Upstream sequence
AAAACATAATAAGCATTTAGTAAATGTTGACTATCAGTGTTAAATACTGTTTACTCTCCAAATAAGTGAGCTGTAATACTTGTGTAATGCTTTCTCACAG
Downstream sequence
GTATGAATTAGGAGCCGCTCTGTTTATTGGATGGGCAGGAGCCTCACTGTGCATAATTGGTGGTGTCATATTTTGCTTTTCAATATCTGACAACAACAAA
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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