Basic Information
VIS ID
TVIS10019792
Fusion event
HBV-chr22 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1802
Integrated sequence
GCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCT| |GCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGC
Host Sequence
Chromosome
chr22
Cytoband
q12.2
Reference genome
GRCh37.55
Start
30102453/29706464 (Hg38)
End
30102453/29706464 (Hg38)
Fragile sites / regions
FRA22B
Nearest miRNA
hsa-mir-1286/Upstream/1246516; hsa-let-7a-3/Downstream/300585;
Nearest TSS
ENST00000624155/Upstream/102465; ENST00000216144/Downstream/13250;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/102300, chr22-CpG: 131/Downstream/13677
Nearby gene
CABP7
Upstream sequence
aggtgcccaggacatatctactcagtgaataaatGAGTGTCTGTTTACCCATCTCGAGCATCTCAGTGCCTGAGAAACTCATCCCACTCCCAGGCTGCTG
Downstream sequence
TGCAATTCAGGTGAAATGATGGCTTGGAAAGGGCTTGTTTTTATAATTAAAATGCAGAGAAGGAGGAAGAGGGAGGCGGTGACTTCCCAGCAAATGGGTG
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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